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Butter vs. palm? tiny study tests Oils' impact on weight

NCT ID NCT04975763

Knowledge-focused Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This small pilot study looks at how eating foods made with soybean oil or palm oil every day for four weeks changes blood fatty acids and body weight in overweight adults. Sixteen participants will try both oils in a crossover design. The goal is to see if people can stick with the diet and whether the oils have different effects on blood fats and weight.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
soybean oil and palm oil
What this could lead to
If successful, this could help understand how different dietary oils affect body weight and blood fat levels, potentially guiding future nutrition advice.
What could go wrong
This is a very small pilot study with only 16 participants, so results may not apply broadly. It is designed to gather preliminary data, not to prove any health benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 16 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2021

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

25 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 25-80 years old * Nonsmokers * BMI 25-55 kg/m2 Exclusion Criteria: * Current or previous diagnosis of heart, kidney, and some liver diseases * Current or previous diagnosis some circulatory diseases and some autoimmune diseases * Treatment of current cancer diagnosis or current cancer diagnosis * Current or previous diagnosis of diabetes * Gastrointestinal diseases or disorders (including pancreatic) that influence nutrient digestion and absorption or gastric bypass surgery * Alcohol or drug abuse * Inability to access veins for venipuncture * Hypothyroidism or Hyperthyroidism diagnosis * Food Allergy or intolerances * Any dietary restriction where consumption of the study foods or any ingredient would be contraindicated * Use of medications where consuming the study foods would be contraindicated * Use of supplements or medications for weight loss or following a weight loss program * Use of supplements high in linoleic acid in the past 4 weeks prior to enrolling * Pregnancy and lactation

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Overweight and obesity

Contacts and locations

Locations

  • The Ohio State University Human Nutrition Laboratory

    Columbus, Ohio, 43210, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.