New hope for celiac sufferers: drug targets gut damage despite Gluten-Free diet

NCT ID NCT07239336

Recruiting now Disease control Sponsor: Chugai Pharmaceutical Source: ClinicalTrials.gov ↗

First seen Nov 20, 2025 · Last updated May 23, 2026 · Updated 24 times

Summary

This study tests a drug called DONQ52 in people with active celiac disease who still have gut damage and symptoms even after trying a gluten-free diet. The goal is to see if the drug can heal the small intestine and reduce symptoms like belly pain and bloating. About 92 adults will take either DONQ52 or a placebo for several weeks, and researchers will measure changes in intestinal health and symptom scores.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Advanced Research Institute
RECRUITING

Reno, Nevada, 89511, United States
Advanced Research Institute
RECRUITING

Ogden, Utah, 84405, United States
Advanced Research Institute Sandy
RECRUITING

Sandy City, Utah, 84070, United States
Akron Gastro Research, LLC
RECRUITING

Akron, Ohio, 44320, United States
Associates in Gastroenterology, PC
RECRUITING

Colorado Springs, Colorado, 80923, United States
Asthma and Allergy Associates, PC
RECRUITING

Colorado Springs, Colorado, 80907, United States
Birmingham Digestive Health Research
RECRUITING

Homewood, Alabama, 35209, United States
California Research Foundation
RECRUITING

San Diego, California, 92123, United States
Care Access Research - Ogden
RECRUITING

Ogden, Utah, 84403, United States
Central Sooner Research
RECRUITING

Norman, Oklahoma, 73071, United States
Chandler Clinical Trials
RECRUITING

Chandler, Arizona, 85224, United States
Clinical Applications Laboratories
RECRUITING

San Diego, California, 92103, United States
Clinical Research Partners, LLC
RECRUITING

Richmond, Virginia, 23226, United States
Columbia Digestive Health Research
RECRUITING

Columbia, South Carolina, 29204, United States
DM Clinical Research - Cyfair Clinical Research Center
RECRUITING

Tomball, Texas, 77375, United States
Digestive Health Research of North Texas
RECRUITING

Wichita Falls, Texas, 76301, United States
Digestive Research of Central Texas, LLC
RECRUITING

Waco, Texas, 76301, United States
East View Medical Research
RECRUITING

Mobile, Alabama, 36608, United States
Encore Borland Groover Clinical Research LLC
RECRUITING

Jacksonville, Florida, 32256, United States
GI Alliance
RECRUITING

Metairie, Louisiana, 70006, United States
GI Alliance -Gurnee
RECRUITING

Gurnee, Illinois, 60031, United States
GI Alliance Rhode Island
RECRUITING

Providence, Rhode Island, 02905, United States
GI Associates Research, LLC
RECRUITING

Columbia, Missouri, 65201, United States
GMC Clinical Research, LLC
RECRUITING

Folsom, California, 95630, United States
Gateway GI Research, LLC
RECRUITING

St Louis, Missouri, 63141, United States
Global Life Research Network
RECRUITING

Miami, Florida, 33155, United States
Great Lakes Gastroenterology Research, LLC
RECRUITING

Mentor, Ohio, 44060, United States
Guardian Angel Research Center
RECRUITING

Tampa, Florida, 33614, United States
Mater
RECRUITING

South Brisbane, Queensland, 4101, Australia
Momentum Clinical Research Dunedin
RECRUITING

Dunedin, Nan, 9016, New Zealand
Mountain View Clinical Research, Inc.
RECRUITING

Denver, Colorado, 80209, United States
Novum Clinical Research
RECRUITING

Clermont, Florida, 34711, United States
Oasis Clinical Research
RECRUITING

Las Vegas, Nevada, 89121, United States
Ocala GI Research
RECRUITING

Ocala, Florida, 34471, United States
Om Research LLC
RECRUITING

Lancaster, California, 93534, United States
One of a Kind Clinical Research Center LLC
RECRUITING

Scottsdale, Arizona, 85258, United States
Pacific Clinical Research Network Hamilton, Waikato
RECRUITING

Hamilton, 3200, New Zealand
Pinnacle Research Group, LLC
RECRUITING

Anniston, Alabama, 36207, United States
Portland Gastroenterology Center
RECRUITING

Portland, Maine, 04101, United States
Research Solutions of Arizona, PC
RECRUITING

Litchfield, Arizona, 85340, United States
Rockford Gastroenterology Associates, Ltd.
RECRUITING

Rockford, Illinois, 61107, United States
Scottsdale Clinical Trials
RECRUITING

Scottsdale, Arizona, 85260, United States
St. Johns Center for Clinical Research
RECRUITING

Saint Augustine, Florida, 32086, United States
Stamford Therapeutics Consortium
RECRUITING

Stamford, Connecticut, 06905, United States
Susquehanna Research Group, LLC
RECRUITING

Harrisburg, Pennsylvania, 17110, United States
Sydney Clinical Trials Pty Ltd
RECRUITING

Campbelltown, New South Wales, 2560, Australia
Texas Medical Center
RECRUITING

Sugar Land, Texas, 77478, United States
Tropical Clinical Trials
RECRUITING

Palmetto Bay, Florida, 33176, United States
University of The Sunshine Coast Clinical Trials Centre (Sippy Downs)
RECRUITING

Sippy Downs, Queensland, 4556, Australia
University of the Sunshine Coast Clinical Trials Centre
RECRUITING

Morayfield, Queensland, 4506, Australia
University of the Sunshine Coast Clinical Trials Centre (SouthBank)
RECRUITING

South Brisbane, Queensland, 4101, Australia
Velocity Clinical Research New Orleans
RECRUITING

New Orleans, Louisiana, 70119, United States
Velocity Clinical Research, Gardena
RECRUITING

Gardena, California, 90247, United States
Velocity Clinical Research, Salt Lake City
RECRUITING

West Jordan, Utah, 84088, United States
Vitality Clinical Research
RECRUITING

Katy, Texas, 77494, United States
Wellness Clinical Research
RECRUITING

Miami Lakes, Florida, 33016, United States

Conditions

Explore the condition pages connected to this study.

CELIAC DISEASE