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Could A2 milk ease gut symptoms in teens with celiac disease?

NCT ID NCT07815821

Symptom relief Sponsor: Halic University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Researchers are testing whether milk and dairy products made with A2 beta-casein protein can improve gut symptoms, quality of life, sleep, and nutritional blood markers in adolescents with celiac disease. The trial enrolls 50 teens aged 10 to 18 who were diagnosed with celiac disease within the past three months. Participants consume either A2-containing milk and dairy products or standard milk and dairy products for eight weeks while completing diet records, symptom and quality-of-life questionnaires, and body composition and blood tests. The goal is to see whether A2 dairy offers extra benefits over standard dairy for this group.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
milk and dairy products containing A2 beta-casein
What this could lead to
If A2 milk helps, it could offer teens with celiac disease a simple dietary option to ease gut symptoms and improve daily quality of life.
What could go wrong
This is a small, short study of 50 teens, and any symptom changes may come from diet or placebo effects rather than A2 protein. Milk products still contain lactose and milk proteins, so they are not safe for teens with lactose intolerance or milk allergy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Feb 2022

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 18 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adolescents aged 10-18 years * Diagnosis of celiac disease according to ESPGHAN criteria * Being diagnosed with celiac disease within the last 3 months * Volunteering to participate in the study Exclusion Criteria: * Presence of any chronic disease other than celiac disease * Presence of lactose intolerance * Presence of cow's milk protein allergy

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Conditions

The condition(s) this trial relates to.

celiac disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

A2 Β-casein-containing milk and dairy products Celiac disease Celiac disease in children

Contacts and locations

Locations

  • Sariyer Hamidiye Etfal Training and Research Hospital

    Istanbul, 34421, Turkey (Türkiye)

More trials for these conditions

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