New supplement trial aims to ease endometriosis pain without drugs
NCT ID NCT07393958
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a food supplement called Doliral can improve quality of life and reduce pelvic pain in women with endometriosis. About 60 women with confirmed endometriosis and ongoing pelvic pain will take either Doliral or a placebo for 12 weeks. Researchers will track changes in pain, daily function, and overall well-being using questionnaires.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Sep 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women of reproductive age with diagnosed endometriosis stage I, II, or III, according to the American Society for Reproductive Medicine (ASRM) classification. * Women with a diagnosis of endometriosis confirmed by laparoscopy or, in the absence of laparoscopy, by magnetic resonance imaging (MRI) and/or ultrasound. * Presence of pelvic pain (VAS \> 4) during the last three months. * No indication for surgical intervention at the time of inclusion in the study. * Patients who are able to provide informed consent. Exclusion Criteria: * Patients under 18 years of age. * Use of analgesic or anti-inflammatory pharmacological treatment, except for ibuprofen at doses up to 600 mg/day or naproxen at doses up to 500 mg/day. * Surgery within the year prior to inclusion, performed for therapeutic purposes related to the pathology under study. * Initiation or discontinuation of hormone therapy within the three months prior to inclusion in the study. * Patients with known allergy or hypersensitivity to Doliral®. * Pregnant or breastfeeding patients. * Patients on sick leave: \> 1 year, or With no intention of returning to work, or Undergoing a disability or permanent incapacity assessment process.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Hospital Clínic de Barcelona
RECRUITINGBarcelona, 08036, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Allergy pill put to the test against endometriosis pain
- Can common endometriosis drugs change blood flow in the brain?
- Can fish oils calm endometriosis inflammation?
- Can surgery save the kidneys in deep endometriosis?
- New imaging tracer could spot hidden cancers and fibrosis in one scan
- Saliva test for endometriosis: will it improve Women's lives?