Calibration check: does Fine-Tuning muscle monitors make a difference?
NCT ID NCT04911088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether calibrating a muscle monitor (EMG) improves how accurately it measures muscle function during anesthesia. 66 adults having surgery took part. The goal was to see if calibration is needed for reliable readings and to find the minimum anesthesia depth required.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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66 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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May 2023
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The CELESTE study will be performed in adult patients scheduled for elective non-cardiac surgery requiring general anesthesia and moderate neuromuscular blockade.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * signed informed written consent * BMI 17.5-30 kg/m\^2 * ASA \<= 3 * supine positioning during surgery with intraoperative access to both arms * absence of allergy to muscle relaxants and reversal agents * absence of neuromuscular disease Exclusion Criteria: * ambulatory patients for whom discharge is planned within 12 hours of anaesthesia * patients undergoing minor surgical * procedures scheduled outside the operating room * patients who are endotracheally intubated prior to surgery * pregnancy * indication for rapid sequence induction * patients undergoing arm surgery * patients with preceding injuries impairing muscle or nerve function of the arm (e.g., finger amputation)
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Ulm
Ulm, Baden-Wurttemberg, 89073, Germany
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Other studies related to the condition(s) this trial covers.
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