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'Natural' cigarette labels may fool smokers into puffing harder

NCT ID NCT05468333

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether cigarette packs labeled 'natural' or 'organic' affect smokers' beliefs about harm, how they smoke, and what chemicals enter their body. Researchers studied 184 daily smokers, including those who smoke Natural American Spirit and other brands. The goal was to see if these labels change smoking behavior or exposure to harmful chemicals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

184 people

The number who actually took part.

Started

Jan 2022

Finished

Aug 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Daily cigarette smoker of 5+ cigarettes/day for at least the past 6 months and consumed 100+ lifetime cigarettes * Smoke non-menthol, filtered cigarettes * Report daily use of any non-Natural American Spirit (NAS) cigarette brand for the last 30 days (for the non-NAS smoker group), or report daily use of NAS cigarettes for at least 30 days (for the NAS smoker group) * Provide exhaled CO level \>= 10 ppm at the Session 1 visit * Able to communicate fluently in English (speaking, writing, and reading) * Capable of providing written informed consent, which includes compliance with the requirements and restrictions listed in human participant protections Exclusion Criteria: * Current use of Nat's cigarettes as a preferred brand * Plan to quit smoking in the next 30 days and not currently undergoing smoking cessation treatment * Are pregnant, planning a pregnancy, and/or lactating * Have any impairment including, but not limited to, visual, physical, and/or neurological impairments preventing the completion of procedures included within this protocol * Have had a serious or unstable disease within the past 6 months (e.g. heart disease, cancer, schizophrenia). * Cannot have ever regularly smoked NAS (for the non-NAS group)

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Conditions

The condition(s) this trial relates to.

Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Desert Research Institute

    Reno, Nevada, 89512, United States

  • University of Nevada, Reno

    Reno, Nevada, 89557, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

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