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'Natural' cigarette labels may fool smokers into puffing harder
NCT ID NCT05468333
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether cigarette packs labeled 'natural' or 'organic' affect smokers' beliefs about harm, how they smoke, and what chemicals enter their body. Researchers studied 184 daily smokers, including those who smoke Natural American Spirit and other brands. The goal was to see if these labels change smoking behavior or exposure to harmful chemicals.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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184 people
The number who actually took part.
- Started
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Jan 2022
- Finished
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Aug 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Daily cigarette smoker of 5+ cigarettes/day for at least the past 6 months and consumed 100+ lifetime cigarettes * Smoke non-menthol, filtered cigarettes * Report daily use of any non-Natural American Spirit (NAS) cigarette brand for the last 30 days (for the non-NAS smoker group), or report daily use of NAS cigarettes for at least 30 days (for the NAS smoker group) * Provide exhaled CO level \>= 10 ppm at the Session 1 visit * Able to communicate fluently in English (speaking, writing, and reading) * Capable of providing written informed consent, which includes compliance with the requirements and restrictions listed in human participant protections Exclusion Criteria: * Current use of Nat's cigarettes as a preferred brand * Plan to quit smoking in the next 30 days and not currently undergoing smoking cessation treatment * Are pregnant, planning a pregnancy, and/or lactating * Have any impairment including, but not limited to, visual, physical, and/or neurological impairments preventing the completion of procedures included within this protocol * Have had a serious or unstable disease within the past 6 months (e.g. heart disease, cancer, schizophrenia). * Cannot have ever regularly smoked NAS (for the non-NAS group)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Desert Research Institute
Reno, Nevada, 89512, United States
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University of Nevada, Reno
Reno, Nevada, 89557, United States
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University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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