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Scientists unmask DMT's secret: trip or biology?

NCT ID NCT06927076

First seen Apr 04, 2026 · Last updated Apr 30, 2026 · Updated 3 times

Summary

This study aims to find out if the antidepressant effect of DMT is due to the psychedelic experience or a direct biological action. 112 adults with moderate-to-severe depression will receive DMT or a placebo, with some receiving a sedative to block the psychedelic effects. Researchers will track changes in depressive symptoms over time.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Basel

    RECRUITING

    Basel, 4031, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.