Could a common solvent make your fillings last longer?
NCT ID NCT07196618
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 27 times
Summary
This study tests whether applying dimethyl sulfoxide (DMSO) to aging teeth before placing a filling improves how well the filling bonds and reduces tiny leaks that can cause decay. Thirty adults aged 50-75 with non-cavity tooth lesions will receive either DMSO or chlorhexidine pretreatment. Their fillings will be checked at 2 weeks, 3 months, and 6 months using standard dental criteria.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Al-Azhar university
Cairo, Egypt
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dimethyl sulfoxide (DMSO)
What this could lead to
If successful, this could lead to a better way to prepare teeth for fillings, making them last longer and reducing the need for repeat dental work.
What could go wrong
This is a small, early-stage study with only 30 participants, so results may not apply to everyone. DMSO may not outperform existing treatments like chlorhexidine.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.