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Can a night cream really tighten skin and smooth wrinkles?

NCT ID NCT07255560

Symptom relief Sponsor: Bionos Biotech S.L. Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a topical cream called DMAE Oleate on 30 healthy adults aged 40 to 55 who had visible fine lines, wrinkles, and loose skin. Participants applied the cream at night for 12 weeks. Researchers measured changes in crow's-feet wrinkles and skin firmness using special devices and asked volunteers how they felt their skin looked. The goal was to see if the cream could improve skin appearance and texture.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
DMAE Oleate (a topical cream)
What this could lead to
If it works, this could point toward a non-prescription cream that helps firm skin and soften fine lines and wrinkles.
What could go wrong
This is a small, early study with only 30 people and no comparison group, so results may not apply to everyone. The product is cosmetic, not a medical treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Sep 2025

Finished

Dec 2025

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 55 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Volunteers with visible signs of fine lines and wrinkles. * Volunteers with visible signs of skin laxity/sagging. * Informed of the purpose and the protocol of the study and signed a written informed-consent form. * Additional criteria to be included by the client. Exclusion Criteria: * Volunteers with sensitive skin. * Pre-existing skin conditions: Eczema, Rosacea. * Pregnancy/breastfeeding/planning pregnancy. * Known allergy/sensitivity to any component of the product. * Agree to avoid excessive sun exposure/self-tanning product/avoid tanning salons/solariums. * No lasers/tretinoin/procedures/facial hair removal/facials 2 weeks prior or during the study. * Additional criteria to be included by the client. * Any condition judged by the investigator to be unsuitable for participation in the study.

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Conditions

The condition(s) this trial relates to.

cutis laxa Fatigue

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Facial wrinkles - rough texture - hyperpigmentation Skin aging of face and hands Skin laxity

Contacts and locations

Locations

  • Bionos Biotech S.L., LabAnalysis Life Science

    Valencia, 46007, Spain

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