Diamond-Infused cream may speed healing after face laser
NCT ID NCT07462533
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a special nanodiamond cream (Pavise ECMR) helps the skin heal better after facial laser treatment for wrinkles and loose skin. Eight adults aged 35-70 will receive the cream on one side of their face and standard care on the other. Researchers will check redness, swelling, crusting, and oozing to see which side heals faster.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 8 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Males or females in good general health age 35-70 years of age. 2. Subjects with score Moderate to Severe (Class II-III, Score 4-9) on the Fitzpatrick-Goldman Classification of Wrinkling and Degree of Elastosis Scale (Appendix E) 3. Subjects with score Moderate to Severe facial photodamage as assessed by the Modified Griffth's Scale (Appendix F) 4. Fitzpatrick skin types I-III. 5. Must be willing to give and sign Informed Consent Form, Photography Release Form and HIPAA Form. 6. The subject must be planning to undergo ablative CO2 and Er:YAG laser resurfacing to the face and willing to comply with study dosing and complete the entire course of the study. 7. Subjects using any skin care products (per physician-investigator discretion) must discontinue use of these products 14 days before treatment and throughout the duration of the study. Subjects will only use the products they are instructed to use by the investigator. 8. Male subjects with facial hair must be willing to shave the morning of the procedure 9. Female patients will be either of non-childbearing potential defined as: Having no uterus or no menses for at least 12 months. Women of childbearing potential must agree to use an effective method of birth control during the study, such as: 1. Hormonal contraception - pill, injection, implant, patch, vaginal ring, Intrauterine device 2. Intrauterine coil 3. Bilateral tubal ligation 4. Barrier method used with an additional form of contraception (e.g., sponge, spermicide or condom) 5. Abstinence (If practicing abstinence must agree to use barrier method described above (4) if becomes sexually active). 6. Vasectomized partner (Must agree to use barrier method described above (4) if becomes sexually active with an Un-Vasectomized partner). 7. Negative urine pregnancy test results at Baseline prior to procedure (if applicable Exclusion Criteria: 1. Pregnant, planning to become pregnant during the course of the study, or breastfeeding. 2. Prescence of an active bacterial, fungal, or viral infection in the treatment area. 3. Significant history or current evidence of a medical, psychological or other condition that, in the investigator's opinion, would preclude enrollment into the study. 4. Use of any topical products containing tretinoins or derivatives, alpha-hydroxy acids, salicylic acid, and vitamins C or E (includes derivatives thereof) on the face within 14 days prior to or during the study period, other than the study products. 5. Receipt of a chemical peel, any systemic steroids, a non-ablative laser, ablative laser, microfocused ultrasound, light or radio frequency treatment, deep chemical peel, or dermabrasion on their face within 6 months prior to study enrollment. 6. Receipt of a microdermabrasion (light or medium skin peel) treatment to the face within 30 days prior to enrollment and unwillingness to refrain from use for the duration of the study period. 7. Excessive exposure to sunlight or artificial UV light (e.g.: use of tanning beds/booths and/or sunbathing) or expectations of tanning during the time of the study or has used self-tanner within 7 days prior to enrollment. 8. Prior treatment with a systemic retinoid within the past 3 months (e.g., Accutane®, Roche Dermatologics). 9. History of keloids or hypertrophic scars. 10. Known allergy to Valacyclovir or Fluconazole or sensitivities to benzocaine, lidocaine, tetracaine, PABA (para-amino benzoic acid), or other local anesthetics of the amide or ester family sedation medication. 11. Presence of tattoo and/or scar in the treatment area that in the investigator's opinion would interfere with study assessments. 12. History of or the presence of any skin condition/disease that might interfere with the diagnosis or evaluation of study parameters (i.e., atopic dermatitis, eczema, psoriasis, seborrheic dermatitis) at the discretion of the physician-investigator 13. Inability to comply with all study protocol restrictions and visits. 14. Current participation or participation within 30 days prior to the start of this study in a drug or other investigational research study. 15. History of non-compliance with clinical research protocols.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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Other studies related to the condition(s) this trial covers.
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