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New drug duo aims to halt hard-to-treat endometrial cancer

NCT ID NCT05761951

First seen Nov 10, 2025 · Last updated Jun 15, 2026 · Updated 28 times

Summary

This early-phase study tests whether combining two drugs, DKN-01 and pembrolizumab, can help control advanced or recurrent endometrial cancer that cannot be cured with surgery or radiation. Eight adult women with this type of cancer will receive the combination. The main goals are to check safety and see how well the treatment works.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

endometrium neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.