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Should heart scans be done right after cardiac arrest? large trial aims to find out

NCT ID NCT02309151

Knowledge-focused Sponsor: Uppsala University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at 1,003 people who had a cardiac arrest outside the hospital and were revived. It compared getting a coronary angiogram (an X-ray of the heart's arteries) within 2 hours versus waiting 3 days. The goal was to see if early imaging improves survival at 30 days. Participants had no clear signs of a heart attack on their first ECG.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Immediate coronary angiography (a procedure to look at heart arteries with X-rays)
What this could lead to
If immediate angiography proves better, it could become the standard approach for cardiac arrest patients without clear heart attack signs, potentially saving more lives.
What could go wrong
This trial is completed but results may not show a clear benefit, and the findings might not apply to all cardiac arrest patients. The procedure itself carries small risks like bleeding or kidney injury.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,003 people

The number who actually took part.

Started

Dec 2014

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Witnessed out of hospital cardiac arrest * Restoration of Spontaneous Circulation (ROSC) \>20 minutes * Coronary angiography is expected to be performed within 120 minutes from inclusion and randomization at hospital Exclusion Criteria: * Patient age \<18 years * Obvious extracardiac genesis of cardiac arrest such as trauma, hemorrhagic shock, and / or asphyxia (eg drowning, suffocation, hanging, exposure to fire smoke) * Terminally ill patients with a life expectancy of less than 1 year * Patients with ST-elevation * Known pregnancy * Patient awake GCS \>8 (Glasgow Coma Scale)

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Conditions

The condition(s) this trial relates to.

cardiac arrest Out-of-Hospital Cardiac Arrest

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Out-of-hospital cardiac arrest

Contacts and locations

Locations

  • Aalborg University hospital

    Aalborg, Denmark

  • Aarhus University Hospital

    Aarhus, Denmark

  • Albert Schweitzer Hospital

    Dordrecht, Netherlands

  • Amsterdam UMC

    Amsterdam, Netherlands

  • Antonius Hospital

    Nieuwegein, Netherlands

  • Catharina Ziekenhuis

    Eindhoven, Netherlands

  • Danderyd Sjukhus

    Stockholm, Sweden

  • Haaglanden Medisch Centrum

    The Hague, Netherlands

  • Karolinska Universitetssjukhuset

    Huddinge, Sweden

  • Karolinska Universitetssjukhuset

    Solna, Sweden

  • Odense University hospital

    Odense, Denmark

  • Radboud University Medical Center

    Nijmegen, Netherlands

  • Sahlgrenska Universitetssjukhuset

    Gothenburg, Sweden

  • Skåne Universitetssjukhus

    Malmö, Sweden

  • Skånes Universitetssjukhus

    Lund, Sweden

  • Södersjukhuset AB

    Stockholm, Sweden

  • Treant Hospital

    Emmen, Netherlands

  • Umeå Universitetssjukhus

    Umeå, Sweden

  • Uppsala University hospital

    Uppsala, 75185, Sweden

  • Zuyderland Hospital

    Heerlen, Netherlands

  • Örebro Universitetssjukhus

    Örebro, Sweden

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