Digital rehab shows promise for long COVID brain fog
NCT ID NCT05846126
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This completed study tested a digital rehab program combining cognitive training, physical exercise, and mindfulness for people with long COVID who have memory and thinking problems. 172 adults with persistent cognitive symptoms at least 12 weeks after COVID-19 took part. The program was delivered remotely or via virtual reality, and researchers measured changes in attention, memory, and processing speed.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- digital rehabilitation program (cognitive training, physical exercise, and mindfulness)
- What this could lead to
- If it works, this could point toward an effective home-based program to improve memory, attention, and thinking in people with long COVID.
- What could go wrong
- This is a completed trial, but results are not yet widely confirmed. The interventions are behavioral, so benefits may vary from person to person.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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172 people
The number who actually took part.
- Started
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May 2023
- Finished
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Dec 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Over 18 years old. * Participants with a diagnosis of COVID-19 presenting persistent neurological symptoms at least 12 weeks after acute infection. * They will have cognitive complaints * Consent from a physician to engage in an exercise intervention Exclusion Criteria: * Established diagnosis before COVID-19 disease of psychiatric, neurological, developmental disorder, or systemic pathologies are known to cause cognitive deficits. * Motor or sensory alterations that impede the rehabilitation program.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Consorci Sanitari de Terrassa
Terrassa, 08227, Spain
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Other studies related to the condition(s) this trial covers.
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