Smart sensors could revolutionize Huntington's monitoring
NCT ID NCT07315984
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see if wearable sensors and digital health tools can accurately track symptoms of Huntington's disease over 12 months. About 75 adults with and without Huntington's will wear sensors on their wrist, ankle, and pendant to measure daily activity, and complete speech, thinking, and movement tests on a tablet. No treatment is given—the goal is to improve how we monitor the disease.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 75 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Jan 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adults with clinical diagnosis of HD, and healthy age-matched controls
- Ages
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25 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female, aged 25-65 years * For HD participants: Genetically diagnosed with HD * Fluent in English (able to speak and read). * Ambulatory without the need for a walking aid. * Able to independently perform all study activities safely, as determined by the investigator. * Willing and able to provide informed consent and comply with all study procedures. For control participants: * Male or female, aged 25-65 years * Clinically assessed to be in good health, with no evidence of neurological disorders that could cause involuntary movements or gait disturbances Exclusion Criteria: * Diagnosis of juvenile-onset HD. * Individuals who are non-ambulatory. * Individuals with a neurological, medical, or psychiatric condition that, in the investigator's judgment, would interfere with safe participation in study activities. * Montreal Cognitive Assessment (MoCA) score of 18 or lower * Pregnant individuals, due to potential changes in gait and physical activity during pregnancy. * Cannot be enrolled into a blinded intervention trial at baseline.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Rochester Medical Center
Rochester, New York, 14642, United States
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Vanderbilt University Medical Center
Nashville, Tennessee, 37212, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a single molecule quiet the genetic chaos behind three brain diseases?
- Can a genetic 'Patch' fix Huntington's disease? lab test aims to find out
- Could a brain disease change behavior years before diagnosis?
- Scientists decode gait signatures to spot brain diseases
- Can a One-Page guide spark better End-of-Life talks for dementia patients?