Can a phone app help prevent heart attacks? new study aims to find out
NCT ID NCT06919302
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a digital heart health program (a web app, online classes, and special foods) added to usual care can lower cholesterol and reduce heart attacks in people with heart disease or risk factors. About 1,100 participants will be randomly assigned to the program or usual care alone and followed for up to 7 years. The goal is to see if technology can help doctors provide better nutrition support and improve heart health.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Digital heart health program (web app, online sessions, and key foods)
- What this could lead to
- If it works, this could provide a practical, scalable way for doctors to help patients improve heart health through diet and lifestyle changes.
- What could go wrong
- This is a large but early-stage behavioral study; results depend on participants sticking with the program, and it may not show clear benefits over standard care alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 1,100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Jun 2035
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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45 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Be taking statin medication with or without other antihyperlipidemic therapy (stable dose for at least 3-months). * Fall under either of the 2 categories: 1\) Secondary prevention participants: males and females ≥45 years of age with established atherosclerotic cardiovascular disease (ASCVD) defined as at least one of the following: i. Prior myocardial infarction (MI); ii. Acute coronary syndrome (ACS); iii. Stroke/TIA; iv. Coronary revascularization; v. Documented carotid disease (endarterectomy, carotid stenosis ≥50%); vi. Stable angina; vii. Coronary artery disease (CAD) by angiography; viii. Peripheral artery disease (PAD); ix. Abdominal aortic aneurysm (AAA) 2\) High-risk primary prevention participants: males and females ≥50 years of age plus type 2 diabetes requiring treatment with medication and at least one additional risk factor: i. Males ≥55 years of age and females ≥65 years of age; ii. Cigarette smoker or stopped smoking within 3 months before Visit 1; iii. Hypertension and on antihypertensive medication for at least 6-months; iv. Chronic kidney disease (CKD); v. Retinopathy, defined as any of the following: non-proliferative retinopathy, pre-proliferative retinopathy, proliferative retinopathy, maculopathy, advanced diabetic eye disease or a history of photocoagulation * Be on a stable dose for at least 3-months of all antihyperlipidemic, antihyperglycemic, antihypertensive, and antiobesity therapies. * Have a family physician in Ontario and a valid Ontario Health Card. * Have regular access to an online portal * Be proficient in English. Exclusion Criteria: * Major disease expected to result in death within 2 years (except cardiovascular disease) * Active sever liver disease * Malabsorption disorders * Drug or alcohol abuse disorders (within past 6 months) * Intolerance or allergies to soy protein and tree nuts, peanuts, or seeds * Planned coronary intervention or any major surgical procedure * Participation in another clinical trial (within past 3 months) * End stage renal disease (requirement for peritoneal dialysis or hemodialysis for renal insufficiency or eGFR \<30 mL/min) * Any condition or therapy which might pose a risk to the patient or make participation in the study not be in the best interest of the patient as assessed by the investigator * Documented severe (New York Heart Association \[NYHA\] class IV) heart failure * Mental/psychological impairment expected to affect adherence to the study protocol * Known AIDS (HIV-positive patients without AIDS are allowed) * Women planning on becoming pregnant within the first year of the intervention * Unable to provide informed consent: Appear unable to comprehend the study protocol during the interview process or to understand and communicate in English sufficiently for informed consent.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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C. David Naylor Building
RECRUITINGToronto, Ontario, M5S1A8, Canada
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