Could a phone app sharpen the minds of people with schizophrenia?
NCT ID NCT07674914
First seen Jun 30, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests a smartphone-based digital training program designed to improve working memory in people with schizophrenia or related disorders. Participants use the app to practice cognitive exercises, and researchers measure changes in memory and mental health. The goal is to see if this easy-to-use tool can help with everyday thinking challenges.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- digital cognitive training program (smartphone app)
- What this could lead to
- If effective, this app could offer a convenient, low-cost way to sharpen thinking skills and improve daily life for people with schizophrenia.
- What could go wrong
- This is an early-stage study with only 45 participants, so results may not apply widely. The app may not produce lasting or meaningful improvements.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 1/2
Runs two stages together: safety and dose first, then whether the treatment works.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * diagnosis of schizophrenia, schizoaffective disorder, or a related psychotic disorder * own a smartphone * English speaking * experiencing challenges with cognitive functioning * no changes to antipsychotic medication in past month Exclusion Criteria: * history of neurological disorder * traumatic brain injury with loss of consciousness \> 10 minutes or behavioral sequelae.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Scientists build a computer model of the brain to explain hearing voices
- Scientists probe brain's reward system in mental illness
- Zapping the Brain's 'Self' switch: can 10 hz current help schizophrenia?
- Brain zaps aimed at two networks may sharpen thinking in schizophrenia
- Can talk therapy and social coaching ease early psychosis?
- Brain training may reshape brain chemistry in schizophrenia