Stress-Busting shake? study tests dairy phospholipids for calmer nerves
NCT ID NCT06109922
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tested whether drinking a whey protein shake containing dairy phospholipids every day for 6 to 12 weeks could help healthy adults cope with stress. 150 people aged 25-49 took either the active drink or a placebo, then completed stressful tasks in the lab. Researchers measured their anxiety, heart rate, and skin responses to see if the supplement improved stress recovery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- whey protein concentrate powder containing phospholipids
- What this could lead to
- If it works, this could point toward a simple dietary supplement to help people feel calmer and recover faster from stress.
- What could go wrong
- This is a small, completed study in healthy adults, so results may not apply to everyone. The effect may be small or no different from placebo.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
150 people
The number who actually took part.
- Started
-
Jan 2024
- Finished
-
Jan 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
25 to 49 years
- Sex
-
Anyone
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant must self-assess themselves as being in good health * Participant must be aged 25 to 49 years at the time of giving consent * Participants first language is English or are fluent in English Exclusion Criteria: * Have any pre-existing medical conditions/illness which will impact taking part in the study. Cases can be looked at case-by-case. * Are currently taking any prescription medications (NOTE the explicit exceptions to this are contraceptive treatments for female participants, and those taking "as needed" in the treatment of asthma and/or hay fever) * Have high blood pressure (systolic over 159 mm Hg or diastolic over 99 mm Hg). NOTE: that we must measure this in the lab using our blood pressure monitors and can only use our measurements to assess eligibility rather than home or doctors readings * Have a Body Mass Index (BMI) outside of the range 18.5-35 kg/m2. * Are pregnant, seeking to become pregnant or lactating. * Have been diagnosed with a neurological condition, or assessed as having a learning/behavioral or neurodevelopmental difference (e.g. dyslexia, autism, ADHD) * Have a visual impairment that cannot be corrected with glasses or contact lenses (including colour-blindness) * Smoke tobacco or vape nicotine or use nicotine replacement products (if you have recently quit smoking or using replacements you must have stopped using them altogether for a period of 3 months before participating in this study) * Have excessive caffeine intake (\>500 mg per day). Note: This will be calculated at screening but feel free to query this with the researcher prior to attendance * Have relevant food allergies/ intolerance/ sensitivities * Have taken antibiotics within the past 4 weeks. * Have taken dietary supplements e.g., vitamins, omega 3 fish oils etc. in the last 4 weeks . (Note: participation is possible following a 4 week wash out prior to participating and for the duration of the study on the proviso that the supplements they are taking are out of choice and not medically prescribed or advised. Please discuss with the researcher if unsure. NOTE: we would never advise stopping supplements prescribed by your doctor e.g. iron, calcium etc, only those out of choice). * Have any health condition that would prevent fulfilment of the study requirements (this includes non-diagnosed conditions for which no medication may be taken) * Are unable to complete all of the study assessments * Are currently participating in other clinical or nutrition intervention studies, or have in the past 4 weeks * Have been diagnosed with/ undergoing treatment for alcohol or drug abuse in the last 12 months. * Have been diagnosed with/ undergoing treatment for a psychiatric disorder in the last 12 months, including a medical diagnosis of anxiety or depression. * Suffers from frequent migraines that require medication (more than or equal to 1 per month) * Have any sleep disorders or take any sleep medications. * Have any known active infections. * Does not have a bank account (required for payment) * Are non-compliant with regards treatment consumption * Follow an "extreme" diet. i.e., high fat, low sugar, low carb, high protein, paleo etc * Are planning a major lifestyle change regarding diet or exercise regime in the next 3 months. * Are unable to meet the minimum requirement scores on the cognitive tasks. * Experienced an event (professional or personal) that is likely to have impacted your emotional and/or psychological state within the last 8-10 weeks (for example but not restricted to change of professional function, death of a family member, divorce, surgery, accident etc) * Have an upcoming event (personal or professional) that is likely to affect your emotional, psychological state or hormonal state planned during the next 8-10 weeks, including but not limited to job change, house move, important medical exam etc. * Have a current diagnosis of renal impairments or phenylketonuria
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MOOD are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northumbria University
Newcastle upon Tyne, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can free groceries and classes rewire daily health habits?
- Can a rewired EMDR therapy ease the mental toll of migration?
- Can beef power firefighter recovery?
- Can a single audio hypnosis session calm exam nerves and boost test scores?
- Can pork protein speed recovery after firefighting?
- Medical Students' stress hormones measured during real patient encounters