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Could a tailored diet quiet the burn of acid reflux?

NCT ID NCT07754721

Symptom relief Sponsor: Hualien Tzu Chi General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 10, 2026 · Last updated Sep 11, 2026 · Updated 3 times

Summary

This trial tests whether personalized dietary guidance from a nutritionist can reduce symptoms of gastroesophageal reflux disease (GERD) better than a standard educational leaflet. Adults with chronic reflux symptoms will receive either tailored advice or written guidelines, and their symptoms, sleep quality, and emotional well-being will be tracked over 12 weeks. The goal is to see if simple dietary changes can offer relief, especially for those whose symptoms persist despite medication.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Personalized dietary guidance from a nutritionist, compared with a written dietary education leaflet
What this could lead to
If effective, this approach could offer a simple, non-drug way to reduce reflux symptoms and improve sleep and daily life for people with GERD.
What could go wrong
The trial is relatively small and relies on self-reported questionnaires, so results may not apply to everyone. Dietary changes may not help those with more complex gut-brain interactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 220 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2025

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 79 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Aged 18-79 years, mentally alert, and willing to provide written informed consent. 2. Individuals with chronic gastroesophageal reflux symptoms (acid regurgitation, chest pain, or heartburn) who are willing to undergo dietary intervention. Exclusion Criteria: 1. Individuals with esophageal stricture, current or prior diagnosis of esophageal tumors, or a history of esophageal, upper gastrointestinal, or pharyngeal surgery. 2. Individuals with structural esophageal disorders (e.g., diverticulum, esophageal rings), infectious esophagitis, or eosinophilic esophagitis. 3. Individuals with major esophageal motility disorders. 4. Individuals taking medications that may affect esophageal motility (e.g., opioids, nitrates, calcium channel blockers). 5. Individuals who have used antidepressants, selective serotonin reuptake inhibitors (SSRIs), or other psychiatric medications continuously within the past three months, or are currently taking them. 6. Pregnant women, or individuals unable to comply with lifestyle and dietary interventions for other reasons.

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Conditions

The condition(s) this trial relates to.

gastroesophageal reflux disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Disorders of gut brain interaction Gastroesophageal reflux disease Lifestyle and dietary interventions

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hualien Tzu Chi Hospital,Buddhist Tzu Chi Medical Foundation

    RECRUITING

    Hualien City, Taiwan, 970, Taiwan

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