Can a special diet and supplements tame inherited high cholesterol?

NCT ID NCT05695937

Completed Disease control Sponsor: Hospital do Coracao Source: ClinicalTrials.gov ↗

First seen Jan 09, 2026 · Last updated May 19, 2026 · Updated 18 times

Summary

This pilot study tested whether a Brazilian heart-healthy diet, with or without added plant sterols and krill oil, can improve cholesterol levels in people with familial hypercholesterolemia (a genetic condition causing very high cholesterol). 58 adults with this condition were randomly assigned to one of four diet groups for 120 days. The main goal was to see if these supplements could lower LDL (bad) cholesterol and lipoprotein(a), a related risk factor.

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Contacts and locations

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Locations

Hcor

São Paulo, Brazil
Hospital Ana Nery

Salvador, Brazil
Hospital São José

Criciúma, Brazil
Hospital das Clínicas da Universidade Federal de Goiás

Goiânia, Brazil
InCor

São Paulo, Brazil
Instituto Dante Pazzanese de Cardiologia

São Paulo, Brazil
Instituto Nacional de Cardiologia

Rio de Janeiro, Brazil
Universidade Feevale

São Leopoldo, Brazil
Universidade Regional do Noroeste do Estado do Rio Grande do Sul

Ijuí, Brazil

Conditions

Explore the condition pages connected to this study.

FAMILIAL HYPERCHOLESTEROLEMIA