Lifestyle changes may boost gut health in melanoma fight
NCT ID NCT04866810
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 41 times
Summary
This study looks at whether a high-fiber, plant-based diet and regular exercise can change the gut microbiome in people with melanoma who are receiving immunotherapy. Researchers want to see if these lifestyle changes are feasible and if they might affect how well the treatment works. The study involves 24 adults and is conducted remotely via phone or video calls.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Loma Linda University
Loma Linda, California, 92350, United States
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National Institutes of Health Clinical Center
Bethesda, Maryland, 20892, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
High-fiber, plant-based diet and exercise prescription
What this could lead to
If successful, this could show that lifestyle changes can influence the gut microbiome and possibly improve outcomes for melanoma patients on immunotherapy.
What could go wrong
This is a small, early feasibility study (24 participants) that is currently suspended. It is designed to test whether the study procedures work, not to prove any health benefits.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.