Plant-Based diet may lower cholesterol in genetic heart condition

This study looked at whether a whole food plant-based diet, low in red and processed meats, can lower LDL cholesterol in 50 adults with heterozygous familial hypercholesterolemia (HeFH), an inherited condition causing high cholesterol. Participants followed both a standard North American diet and the plant-based diet in a crossover design. Researchers also used blood tests to find a unique pattern (metabolomic signature) that shows if someone is sticking to the healthy diet. The goal is to better manage heart disease risk in people with HeFH.