4-Week vegan diet tested as CLL therapy
NCT ID NCT07487428
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a 4-week whole-food plant-based diet can improve immune function and slow disease activity in people with early-stage chronic lymphocytic leukemia (CLL) who have not yet received treatment. Fifty participants will follow the diet and provide blood and stool samples before, during, and after the diet period. Researchers will measure changes in lymphocyte counts and immune cell metabolism.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- whole-food plant-based diet
- What this could lead to
- If it works, this could point toward a dietary approach to help manage early-stage CLL without immediate drug treatment.
- What could go wrong
- This is a small, early-phase study with only 50 participants and no control group. The diet is short-term, so any effects may be temporary or not clinically meaningful.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Confirmed CLL diagnosis * No previous treatments (watch and wait) * Willingness to comply to a whole-food plant-based diet for 4 weeks * Willingness to participate in a total of 3 blood drawings Exclusion Criteria: * Emergency interventions * Patients that already follow a WFPB or vegan diet * Progression of CLL that implicates need for treatment * Insulin-dependent diabetes * Taking lipid-lowering medications (e.g. statins) * Body mass index (BMI) \<20 And if in the opinion of the investigator there are any concerns regarding the ability of the patient to complete the study safely.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Klinikum der Technischen Universität München (Klinikum rechts der Isar)
RECRUITINGMünchen, Bavaria, 81676, Germany
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