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Does fatty food throw off your Body's clock? new study investigates

NCT ID NCT04743271

Knowledge-focused Sponsor: Oregon Health and Science University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how eating a high-fat diet can change your body's internal clock, which controls sleep and other daily rhythms. Researchers will track 14 healthy, lean adults over 46 days, including 18 days spent in a research center. The goal is to understand how quickly the body adjusts to a high-fat diet and how this affects sleep patterns.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 14 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2022

Expected to finish

Mar 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy, lean men and women Exclusion Criteria: * Major dietary restrictions (such as entirely dairy-free and/or meat-free diets) * A body mass index (BMI) of 18.5\< \[BMI\] \< 24.9 kg/m\^2 and a waist circumference \<94/80cm * Currently psychiatrically/psychologically unsuitable for participation * Drug/alcohol use, including smoking * Medication/drug use, including prescribed and over-the-counter medications * History of working irregular day and night hours, regular night work, or rotating shift work for the 1 year prior to the study. * Traveled across more than 1 time zone during the 3 months prior to the study * Currently consuming a habitual high-fat diet * Chronobiologic and sleep disorders * Diseases of the Cardiovascular System * Metabolic Syndrome; Two or more of these factors will be excluded from the study: 1. HDL cholesterol of less than 40 mg/dL in men or less than 50 mg/dL in women; 2. systolic blood pressure\>135 mmHg or diastolic blood pressure\>85 mmHg; 3. Fasting blood glucose ≥ 100 mg/dL; 4. Triglycerides ≥ 150 mg/dL. * Pre-Diabetes/Diabetes * Hypertension * Disorders of the Respiratory System * Disorders of the Kidney and Urinary Tract * Infectious Diseases * Disorders of the Gastrointestinal System * Disorders of the Immune System * Disorders of the Hematopoietic System * Neoplastic Diseases * Endocrine and Metabolic Diseases * Neurologic Disorders * Subjects must not be currently participating in another research study that would influence their safe participation in our study

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Conditions

The condition(s) this trial relates to.

circadian rhythm sleep disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Circadian rhythm Diet, high-fat

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Oregon Health & Science University

    RECRUITING

    Portland, Oregon, 97239, United States

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