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Ultrasound of breathing muscle may predict ventilator weaning success

NCT ID NCT07332403

Knowledge-focused Sponsor: Fatih Sultan Mehmet Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether ultrasound measurements of the diaphragm, the main breathing muscle, can help predict if ICU patients on ventilators will successfully breathe on their own. Researchers measured diaphragm thickness and movement in 60 patients before removing the breathing tube. The goal was to see if these measurements could tell doctors which patients would succeed and which might need more support.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple bedside test to help doctors decide when to safely remove a breathing tube.
What could go wrong
This is a small, completed observational study. The results may not apply to all ICU patients, and ultrasound measurements can vary between users.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Mar 2025

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients who were admitted to the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital between March 2025 and December 2025, received invasive mechanical ventilation for at least 24 hours, and were considered ready for separation from mechanical ventilation by the intensive care physician.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Patients who were admitted to the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital between March 2025 and December 2025, received invasive mechanical ventilation for at least 24 hours, and were considered ready for separation from mechanical ventilation by the intensive care physician. 2. Patients aged 18 years and older. 3. Patients who provided written informed consent. Exclusion Criteria: 1. Patients younger than 18 years of age. 2. Patients with a tracheostomy, neuromuscular disease, diaphragmatic paralysis, or spinal cord injury above the T8 level. 3. Patients with pneumothorax, pneumomediastinum, or chest wall and/or diaphragmatic injury. 4. Patients for whom informed consent could not be obtained.

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Conditions

The condition(s) this trial relates to.

diaphragm disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Assesment of diaphragmatic function by ultrasound to predict weaning success in mechanical ventilated intensive care unit patients Diaphragm usg Intensive care (ICU) Ultrasonography Weaning mechanical ventilation

Contacts and locations

Locations

  • Fatih Sultan Mehmet Training and Research Hospital

    Istanbul, Turkey (Türkiye)

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