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Dialysis duration linked to bladder shrinkage in kidney patients

NCT ID NCT07570771

Knowledge-focused Sponsor: Sindh Institute of Urology and Transplantation Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study looks at how long a person has been on dialysis and how much urine they still make affects bladder size and flexibility. Researchers will measure bladder function in 87 adults with kidney failure who are waiting for a transplant. The goal is to find bladder problems early to improve transplant success.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help doctors better prepare kidney transplant patients by identifying bladder problems early, potentially reducing post-transplant complications.
What could go wrong
This is an observational study, not a treatment trial. It only measures bladder function and does not test any new therapy, so it cannot directly improve patient outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 87 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2026

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients with end-stage renal disease (ESRD) on maintenance dialysis and awaiting renal transplantation at Sindh Institute of Urology and Transplantation (SIUT), Karachi.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD) * Patients on maintenance dialysis for a duration of 6 to 24 months * ESRD secondary to non-urological causes * Patients awaiting renal transplantation Exclusion Criteria: * Patients with diabetes mellitus * Patients with neurogenic bladder * Patients with prior urological surgeries * Patients with active urinary tract infection * Patients with pre-existing lower urinary tract symptoms before dialysis * Patients on medications affecting lower urinary tract function * Patients with neurological or systemic diseases affecting bladder function

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Conditions

The condition(s) this trial relates to.

end stage renal failure urinary bladder disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bladder dysfunction End-stage renal disease requiring haemodialysis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Sindh Institute of Urology and Transplantation (SIUT)

    RECRUITING

    Karachi, Sindh, 74200, Pakistan

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