Fish oil pills may boost attention in ADHD children, small study hints
NCT ID NCT07521449
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether phosphatidylserine supplements with or without DHA (an omega-3 fat) could improve thinking skills in children with ADHD. 45 children aged 10-14 who had never taken ADHD medication took either a placebo or one of three supplement formulas daily for 8 weeks. Researchers measured attention, impulsivity, and hyperactivity using computer tests before and after the treatment.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Phosphatidylserine and DHA (omega-3) supplements
- What this could lead to
- If it works, this could point toward a natural supplement option to help children with ADHD focus better without medication.
- What could go wrong
- This is a small, early-stage trial with only 45 children. The results may not apply to all kids with ADHD, and supplements are not a substitute for proven treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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45 people
The number who actually took part.
- Started
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Dec 2023
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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10 to 14 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 10-14 years * Diagnosis of ADHD according to DSM-5 criteria or clinically significant subthreshold ADHD symptoms * Medication-naïve status * Ability to complete cognitive assessments (MOXO d-CPT and Stroop test) * Informed consent obtained from parents or legal guardians Exclusion Criteria: * Presence of psychiatric disorders requiring pharmacological treatment (e.g., major depressive disorder, severe anxiety disorders, autism spectrum disorder) * Neurological or sensory impairments affecting test performance * Use of cognitive-enhancing supplements (e.g., omega-3, phosphatidylserine, citicoline) within the previous 8 weeks * Severe ADHD requiring immediate pharmacological treatment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul Aydin University, Department of Child and Adolescent Psychiatry, Istanbul, Turkey
Istanbul, Istanbul, 34295, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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