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Can algae oil help set Omega-3 guidelines? new study investigates

NCT ID NCT06294067

Knowledge-focused Sponsor: University of Toronto Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed Phase 1 trial tested different doses of DHA (an omega-3 from algae oil) in 72 healthy vegetarians and vegans over 8 weeks. Researchers measured changes in blood EPA levels to understand how the body processes these fats. The goal is to provide data that could help set official dietary recommendations for DHA.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
docosahexaenoic acid (DHA) from algae oil
What this could lead to
If successful, this study could help set official dietary recommendations for DHA, potentially reducing overconsumption of omega-3s from fish.
What could go wrong
This is a small, early-phase study in healthy people, so results may not apply to the general population or lead directly to new guidelines.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 1

The first testing in people. Mainly checks safety and dose, usually in a small group.

Participants

72 people

The number who actually took part.

Started

Feb 2024

Finished

Mar 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy vegans or vegetarians who do not consume meat or fish. Exclusion Criteria: * Has regularly consumed EPA and/or DHA supplements within the past six months * Having 3% or higher of DHA in their total plasma lipids * BMI \<18 kg/m2 or \>30 kg/m2 * Menopausal or post-menopausal * Pregnant or breastfeeding * Has a chronic or communicable diseases (like multiple sclerosis, kidney and inflammatory bowel disease, Type 2 diabetes, cancer or heart disease) * Suffers from acute or chronic infections, use of chronic anti-inflammatory medication, use of lipid-controlling medication, hypertriglyceridemia (\>4 mmol/l) or hypercholesterolemia (LDL-C \>5 mmol/l) * Anticipates major changes in lifestyle * Is a smoker * Is a heavy alcohol user (\>3 drinks/day) * Has had a major surgery involving organs like open heart surgery or organ transplants in the last six months * Is or has participated in an intervention trial in the last six months

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nutrition, healthy

Contacts and locations

Locations

  • Clinical Nutrition and Risk Factor Modification Centre

    Toronto, Ontario, M5C 2T2, Canada

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