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Vitamin B5 injections could speed up chronic wound healing

NCT ID NCT07395674

Disease control Sponsor: Dilara CANBAY OZDEMIR Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study tests whether injecting dexpanthenol (a vitamin B5 derivative) under the skin around chronic wounds can help them heal faster. 40 adults with diabetic foot ulcers, venous leg ulcers, or arterial ulcers will receive either standard wound care alone or standard care plus dexpanthenol injections. The study will measure changes in wound size and skin regrowth over time.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dexpanthenol (vitamin B5 derivative)
What this could lead to
If it works, this could offer a simple injection to help chronic wounds heal faster, reducing pain and infection risk.
What could go wrong
This is a very small pilot study (40 people) with no phase. Results may not apply to all wound types, and injections could cause local reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Dec 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 years and older. * Presence of a chronic wound, including diabetic foot ulcer, venous leg ulcer, or arterial ulcer. * Target wound size between 1 and 20 cm² at baseline. * Non-infected wound, defined by the absence of purulent discharge, foul odor, spreading erythema, cellulitis, or systemic signs of infection. * Clinically stable patients without the need for systemic antibiotic therapy. * Ability to understand the study procedures and provide written informed consent. * Willingness and ability to comply with study visits and treatment schedule. Exclusion Criteria: * Clinical signs of wound infection or requirement for systemic antibiotic treatment. * Critical limb ischemia, defined as ankle-brachial index \<0.5, rest pain, gangrene, or extensive tissue necrosis. * Wounds exposing bone, tendon, or joint structures, or suspected osteomyelitis. * Wound size smaller than 1 cm² or larger than 20 cm². * Malignant, autoimmune, vasculitic, or specific dermatologic conditions causing the wound. * Known hypersensitivity or allergy to dexpanthenol or any component of the study treatments. * Pregnancy or breastfeeding. * Cognitive impairment or inability to provide informed consent. * Participation in another interventional clinical trial that could interfere with the outcomes of this study. * Any medical condition that, in the investigator's judgment, could compromise participant safety or study integrity.

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Conditions

The condition(s) this trial relates to.

Diabetic Foot ulcer of lower limbs Varicose Ulcer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Arterial ulcer Chronic wounds Diabetic foot ulcer Venous leg ulcers

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Ordu University Training and Research Hospital

    Ordu, Ordu, 52200, Turkey (Türkiye)

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