New hydrogel patch could make scrapes heal faster and hurt less
NCT ID NCT07642973
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test a special hydrogel patch containing dexpanthenol (a form of vitamin B5) on small, controlled scrapes in 40 healthy adults. Each person will have two identical scrapes on their forearms: one treated with the new patch and the other with a standard plaster. Researchers will compare how quickly the wounds close, pain levels, and scar quality to see if the medicated patch offers any advantage.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexpanthenol
- What this could lead to
- If it works, this could lead to a better, less painful way to heal minor scrapes and cuts at home.
- What could go wrong
- This is a very early, small trial on healthy volunteers, not real wounds. The patch may not prove better than a standard plaster in everyday use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 64 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy male or female volunteers aged 18 to 64 years (inclusive). * Informed consent form signed voluntarily before any study-related procedure. * Subjects willing and able to comply with all study protocol requirements, including scheduled visits and home-wear restrictions. * Intact, healthy skin on both volar forearms (free of tattoos, scars, sunburns, or active skin lesions in the designated test areas). * Agree to take precautions to prevent pregnancy (applicable only to non-menopausal women), including abstinence, intrauterine devices (IUDs), progestogen implants, combined estrogenic-progestogen contraceptives, the use of condoms; Exclusion Criteria: * Known hypersensitivity or allergy to Dexpanthenol, hydrogel components, acrylic adhesives, or any component of the investigational devices. * History of keloid formation, hypertrophic scarring, or abnormal wound healing. * Active dermatological conditions (e.g., psoriasis, eczema, atopic dermatitis, active infections) on the upper extremities. * History of diabetes mellitus, peripheral vascular disease, or arterial/venous microangiopathy. * Systemic treatment with corticosteroids, immunosuppressive drugs, Anticoagulants, antiplatelet agents or cytostatic agents within 4 weeks prior to Baseline, or anticipated need during the study. * Topical treatment (steroids, retinoids, antibiotics, or moisturizers) applied to the volar forearms within 2 weeks prior to Baseline. * Active heavy smokers (more than 10 cigarettes per day) or users of nicotine-replacement therapies (nicotine alters cutaneous microcirculation and significantly impairs wound healing kinetics) * Pregnant or lactating women, or women of childbearing potential not using highly effective contraception (see inclusion criteria). * Not willing and able to comply with all study protocol requirements
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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la U.O.C. Anestesia Rianimazione degli Ospedali Riuniti Padova Sud
Monselice, PD, 35043, Italy