Calmer recovery: which sedative works best after sinus surgery?
NCT ID NCT07392983
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two common sedatives, dexmedetomidine and midazolam, to see which one better prevents confusion and agitation after sinus surgery. 146 adults having functional endoscopic sinus surgery took part. The goal was to find a way to help patients wake up more calmly.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
146 people
The number who actually took part.
- Started
-
Jul 2025
- Finished
-
Dec 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
16 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Any gender * Aged 16-60 years * Undergoing elective FESS under general anesthesia Exclusion Criteria: * Patients with the presence of infection at the site of the blockage * Epilepsy, myasthenia gravis, or polio (as per history and clinical record) * Systemic illness (such as cardiac, hepatic, endocrinal or neurological) * Substance induced disorder * Psychiatric disorders * Taking medications, such as alpha 2 agonists, beta blockers' or tricyclic anti-depressants * Allergies to the medications used
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Emergence agitation are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bahawal Victoria Hospital/Quad-e-Azam Medical College
Bahawalpur, Punjab Province, 63100, Pakistan
-
Bahawal Victoria Hospital/Quid-e-Azam Medical College
Bahawalpur, Punjab Province, 63100, Pakistan
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a safer opioid choice stop Kids' Post-Surgery agitation?
- Can a lighter sedative dose keep patients calm after nasal surgery?
- Virtual reality could replace sedatives for anxious hip surgery patients
- Can a Mother's lullaby calm children after anesthesia?
- Nose nerve block calms Post-Surgery agitation, study finds
- New study aims to calm kids after surgery with smarter anesthesia