Can a simple IV drug stop post-surgery agitation? new trial aims to find out.
NCT ID NCT07355049
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test two different medicines given through a vein to see which one better prevents confusion and agitation when waking up from sinus surgery. About 80 adults having planned sinus surgery will take part. Each person will get either dexmedetomidine or lidocaine, and doctors will watch for signs of agitation and check heart rate.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Feb 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age : 18-60 * ASA Physical Status I or II * Elective endoscopic sinus surgery under general anesthesia . Exclusion Criteria: * Refusal to participate * Mental retardation or inability to communicate * Allergy to anesthetics or study medications . * Chronic use of beta blockers . * significant hepatic, neurologic, cardiovascular or respiratory disease . * BMI\>35 kg/m2
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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FayoumU
Al Fayyum, 63511, Egypt
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Other studies related to the condition(s) this trial covers.
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- Nose nerve block calms Post-Surgery agitation, study finds
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