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Melatonin plus sedative may prevent brain surgery confusion

NCT ID NCT07475156

First seen Mar 24, 2026 · Last updated Apr 29, 2026 · Updated 4 times

Summary

This study tested whether adding melatonin to a standard sedative (dexmedetomidine) could lower the chance of post-operative delirium—sudden confusion—after open brain surgery. 100 adults aged 30-60 with brain lesions or hematomas took part. Researchers measured confusion using standard scoring tools.

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Contacts and locations

Locations

  • Faculty of Medicine , Ain Shams University

    Cairo, Abbassia, 1181, Egypt

Conditions

Explore the condition pages connected to this study.