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Brain surgery aftermath: new drug combo may clear the fog

NCT ID NCT07475156

First seen Mar 24, 2026 · Last updated Jun 14, 2026 · Updated 14 times

Summary

This study tested whether adding melatonin to a standard sedative (dexmedetomidine) could lower the chance of post-operative delirium—sudden confusion and disorientation—after open brain surgery. 100 adults aged 30-60 with brain lesions or hematomas took part. Researchers measured delirium using standard scoring tools. The goal was to find a safer, more effective way to help patients recover clearly.

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Contacts and locations

Locations

  • Faculty of Medicine , Ain Shams University

    Cairo, Abbassia, 1181, Egypt

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.