New nerve block cocktail aims to ease shoulder surgery pain
NCT ID NCT07626346
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding dexmedetomidine to the numbing drug bupivacaine in a nerve block can improve pain control after shoulder surgery. About 84 adults having laparoscopic shoulder surgery will be randomly assigned to receive either the drug combo or bupivacaine alone. The main goal is to see how long pain relief lasts and whether it reduces the need for additional painkillers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- dexmedetomidine added to bupivacaine
- What this could lead to
- If it works, this could provide longer-lasting pain relief after shoulder surgery and reduce the need for opioids.
- What could go wrong
- This is a small, early-stage trial with only 84 participants. The added drug may not improve pain control and could cause side effects like low blood pressure or slow heart rate.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 84 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Male or female patients aged 18-65 years 2. Patients Undergoing laparoscopic shoulder surgeries (shoulder arthroplasties and shoulder endoscopic surgeries ) 3. American Society of Anesthesiologists (ASA) physical status I-II Exclusion Criteria: 1. Patient refusal. 2. hypersensitivity or contraindication to dexmedetomidine 3. History of allergy or intolerance to study medications 4. Chronic opioid use (\>3 months) 5. Pregnancy or breastfeeding 6. Severe renal or hepatic impairment 7. Patient's with coagulopathy disorders
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kasr Alainy
RECRUITINGCairo, Egypt
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