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New pain block combo tested for cancer surgery recovery

NCT ID NCT06130670

Symptom relief Sponsor: Assiut University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether adding dexmedetomidine to the numbing drug bupivacaine improves pain relief after lower abdominal cancer surgery. Researchers compared two types of nerve blocks: quadratus lumborum and epidural. Fifty-four adults aged 18–70 participated. The main goal was to see how long pain relief lasted before patients needed more pain medicine.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexmedetomidine added to bupivacaine
What this could lead to
If it works, this could point toward a better way to manage pain after major cancer surgery, possibly reducing the need for strong opioids.
What could go wrong
This is a small, completed study with only 54 participants. Results may not apply to all patients, and the best block type is still uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

54 people

The number who actually took part.

Started

Apr 2024

Finished

Dec 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. patient's 18-70years old 2. ASA I-II and NYHA I-II. 3. type of surgery: major lower abdominal cancer surgery Exclusion Criteria: 1. Patients who refused to participate in the study. 2. coagulation disorders. 3. opioid dependence. 4. sepsis or local infection at or near the vicinity of the block site. 5. patients with psychiatric illnesses that would interfere with perception and assessment of pain. 6. allergy to any of the studied drugs.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

To compare efficacy of dexmedetomidine in bilateral quadratus lumborum VS lumbar epidural blocks on analgesia after major lower abdominal surgery

Contacts and locations

Locations

  • Assiut University

    Asyut, Egypt