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Dental implant pain: which drug works best?

NCT ID NCT02763059

Symptom relief Sponsor: King Abdulaziz University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study tested whether ibuprofen or dexamethasone is better at preventing pain after getting a dental implant. 132 adults received one of the drugs or a placebo before surgery. Pain levels were tracked for several days after. The goal is to find the most effective way to keep patients comfortable.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone and ibuprofen
What this could lead to
If this trial shows one drug works better, it could help dentists choose the most effective painkiller for implant surgery.
What could go wrong
This is a small, completed Phase 4 trial with 132 participants. Results may not apply to everyone, and both drugs have side effects like stomach upset or increased infection risk.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

132 people

The number who actually took part.

Start date

Sep 2013

Finished

Feb 2016

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Informed consent for the described procedure * Surgical placement of a single endosteal implant * Age of at least 18 years Exclusion Criteria: * The need for bone grafting or sinus lift for implant placement * Pregnant and lactating women * Metabolic disorders * Immunocompromised status * Hemophilia or bleeding disorders * Drug or alcohol abuse * Treatment with steroids in the previous 6 months * History of radiation therapy in the head and neck * Psychiatric disorders * Inability to understand the procedure described in the questionnaire

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pain measurement

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