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Steroid soak on breathing tube may stop Post-Surgery sore throat

NCT ID NCT07823192

Prevention Sponsor: KRL Hospital, Islamabad Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 16, 2026 · Last updated Sep 17, 2026 · Updated 1 time

Summary

Researchers test whether soaking the breathing tube in a steroid solution before surgery can prevent sore throat after gallbladder removal. Adults having elective laparoscopic cholecystectomy receive a tube soaked in either dexamethasone or saline. The team checks for sore throat 24 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone, a steroid drug
What this could lead to
If it works, this could offer a simple, low-cost way to prevent sore throat after surgery, improving comfort for patients who need a breathing tube.
What could go wrong
The trial is small and early-stage, so results may not hold up in larger groups. Dexamethasone can raise blood sugar, so it may not suit everyone, and the tube-soaking method may not deliver enough drug to make a difference.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 2

Tests whether the treatment actually works, and watches for side effects, in a larger group.

Participants

About 64 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients undergoing general anesthesia requiring ETT insertion during elective laparoscopic cholecystectomy. * ASA I \& ASA II patients * Patients consenting to be a part of the study Exclusion Criteria: * Patients having diabetes mellitus * Patients with suspected or incidental difficult Intubation

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post operative sore throat

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

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Contacts and locations

Locations

  • KRL Hospital Islamabad

    Islamabad, 44000, Pakistan

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