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One dose before surgery: could a common steroid shield mothers from spinal Anesthesia's biggest risk?

NCT ID NCT07761585

Prevention Sponsor: Liaquat National Hospital & Medical College Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a single intravenous dose of dexamethasone, given before spinal anesthesia, can prevent low blood pressure (spinal hypotension) in women having an elective cesarean section. Low blood pressure after spinal anesthesia is common and can cause nausea, dizziness, and reduced blood flow to the baby. Researchers will compare dexamethasone against a placebo, monitoring blood pressure during surgery and tracking the need for additional blood-pressure-raising medications.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If effective, this simple pre-surgery dose could reduce a common complication of C-sections, improving safety and comfort for mothers and babies.
What could go wrong
This is a small, early-stage trial, and results may not apply broadly. Dexamethasone may not prevent hypotension, and any drug in pregnancy carries potential risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

80 people

The number who actually took part.

Started

Feb 2026

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant females Consenting No contraindications Exclusion Criteria: * Non consenting

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Caesarian section

Contacts and locations

Locations

  • Liaquat National Hospital

    Karachi, Pakistan