One dose before surgery: could a common steroid shield mothers from spinal Anesthesia's biggest risk?

NCT ID NCT07761585

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial tests whether a single intravenous dose of dexamethasone, given before spinal anesthesia, can prevent low blood pressure (spinal hypotension) in women having an elective cesarean section. Low blood pressure after spinal anesthesia is common and can cause nausea, dizziness, and reduced blood flow to the baby. Researchers will compare dexamethasone against a placebo, monitoring blood pressure during surgery and tracking the need for additional blood-pressure-raising medications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexamethasone
What this could lead to
If effective, this simple pre-surgery dose could reduce a common complication of C-sections, improving safety and comfort for mothers and babies.
What could go wrong
This is a small, early-stage trial, and results may not apply broadly. Dexamethasone may not prevent hypotension, and any drug in pregnancy carries potential risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Liaquat National Hospital

    Karachi, Pakistan