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Could a simple steroid ease Post-C-Section pain?

NCT ID NCT07257406

Symptom relief Sponsor: Valerie Zaphiratos Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 06, 2026 · Updated 2 times

Summary

This study looked at whether giving a single dose of the steroid dexamethasone after a cesarean delivery can reduce pain and improve recovery. 87 women who had a planned C-section under spinal anesthesia received either dexamethasone or a placebo right after delivery. Researchers measured pain scores when patients first got out of bed, about 6 hours after surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Dexamethasone
What this could lead to
If effective, this could offer a low-cost, low-side-effect option to improve pain control after cesarean delivery.
What could go wrong
This is a small, completed trial with 87 participants, so results may not apply to all patients. Dexamethasone may not significantly reduce pain compared to standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

87 people

The number who actually took part.

Started

Sep 2018

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age ≥ 18 years * Cesarean delivery * Planned spinal or combined neuraxial anesthesia * Presence of an investigator in the delivery room * Pregnancy \> 34 weeks gestation Exclusion Criteria: * Cesarean delivery under general anesthesia * Inability to understand French or English * Allergy or hypersensitivity to dexamethasone * Allergy to hydromorphone * Allergy to NSAIDs * Acute kidney injury or chronic kidney failure * Preeclampsia * Extremely urgent cesarean section * Urgent cesarean section with non-reassuring fetal monitoring * Known maternal heart disease * High-grade placental abnormality * Diabetes (pregnancy or pre-existing) * Systemic infection, sepsis, fever * Regular use of dexamethasone in the last year * Weight greater than 120 kg and less than 70 kg * Height less than 150 cm * Chronic pain and/or chronic use of opioids

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Conditions

The condition(s) this trial relates to.

Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cesarean delivery Dexamethasone Pregnancy

Contacts and locations

Locations

  • CHU Sainte-Justine

    Montreal, Quebec, H2V 4K8, Canada

More trials for these conditions

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