Knee replacement patients may need fewer opioids with right steroid dose
NCT ID NCT06715709
First seen Feb 06, 2026 · Last updated May 23, 2026 · Updated 18 times
Summary
This study looks at how many doses of the steroid dexamethasone work best for people having knee replacement surgery. The goal is to reduce pain, the need for strong painkillers (opioids), and nausea after the operation. About 339 adults having their first knee replacement will take part. Researchers will compare different dosing schedules to find the safest and most effective option.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States
Conditions
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