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Which anesthetic wakes seniors faster after surgery?

NCT ID NCT07289945

Symptom relief Sponsor: Hopital Charles Nicolle Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study tested two common anesthesia drugs, desflurane and sevoflurane, in 81 elderly patients (60+) having non-cardiac surgery. The goal was to see which drug helps patients wake up and recover their thinking skills faster after surgery. Researchers measured how quickly patients opened their eyes, followed commands, and were ready to leave the recovery room.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

81 people

The number who actually took part.

Started

Sep 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Elderly patients whose ages are superior to 60 years of age \[1\]. * Patients with an American Society of Anesthesiologists Classification (ASA) I, II or III stable (Annex 1). * Patients undergoing elective non-cardiac surgery under general anesthesia with tracheal intubation. Non-inclusion criteria: * Patients having declined to participate in the study protocol. * Patients with a contraindication for minimal flow anesthesia such as hyperthermia, smoke intoxication and ketoacidosis metabolic condition (for example, anorexia nervosa). * Patients with history of malignant hyperthermia. * Patients with Psychotic disorders. * Patients with substance abuse. * Patients with severe obstructive or restrictive pulmonary disease. * Patients with hepatic disease. * Patients with end stage renal disease. * Patients with history of allergy to study drugs. Exclusion Criteria: * We excluded from our study patients who presented with perioperative complication or instability requiring ICU transfer due to extubation failure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive function Early recovery in elderly patients

Contacts and locations

Locations

  • Hospital of Charles Nicolle, Tunis, Tunis 1006

    Tunis, Tunis Governorate, 1006, Tunisia

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