Anesthesia showdown: which drug is kinder to the optic nerve?
NCT ID NCT07359508
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed Phase 4 trial looked at how two common anesthetics—desflurane and propofol—affect the optic nerve sheath diameter (a measure of pressure around the eye) in 146 adults undergoing laparoscopic gallbladder removal. The goal was simply to observe differences between the two drugs, not to treat any disease. The study provides knowledge about anesthetic effects but does not aim to cure or control a condition.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- desflurane and propofol
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
146 people
The number who actually took part.
- Started
-
Jan 2024
- Finished
-
Jul 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 60 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patient aged 18-60 years ASA grade I or II scheduled for elective laparoscopic cholecystectomy Exclusion Criteria: * patients with ophthalmological and cerebrovascular diseases, systemic infections, psychiatric disorders, pregnancy, Intracranial space occupying lesion, abnormal liver/kidney functions prior myocardial infarction.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
AIIMS
Raebareli, Uttar Pradesh, 229405, India
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Other studies related to the condition(s) this trial covers.
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