New imaging tricks could end guesswork for hand and foot skin conditions
NCT ID NCT07626697
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 81 adults with either palmoplantar psoriasis or palmoplantar eczema, two skin conditions that can look very similar on the palms and soles. Researchers used two special camera techniques—polarized dermoscopy and ultraviolet-induced fluorescence dermoscopy—to see if they could spot differences between the two diseases. The goal is to help doctors make a faster, non-invasive diagnosis without needing a skin biopsy.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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81 people
The number who actually took part.
- Started
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Nov 2025
- Expected to finish
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Jul 2026
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
A total of 81 adult patients aged 18 years and older with clinically and/or histopathologically confirmed palmoplantar plaque psoriasis or palmoplantar eczema were included. Participants were recruited from the dermatology outpatient clinic of a tertiary care training and research hospital.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18 years or older. * Clinical diagnosis of palmoplantar psoriasis or palmoplantar eczema involving the palms and/or soles. * For the palmoplantar psoriasis group: presence of sharply demarcated erythematous and scaly plaques on the palms and/or soles, with diagnosis confirmed clinically and/or histopathologically. * In clinically uncertain palmoplantar psoriasis cases, at least one supporting feature such as psoriatic lesions outside the palmoplantar area, psoriatic nail involvement, psoriatic arthritis, personal history of psoriasis, or family history of psoriasis. * For the palmoplantar eczema group: presence of chronic or recurrent palmoplantar eczema with hyperkeratotic and/or fissured palmoplantar plaques, with diagnosis confirmed clinically and/or histopathologically. * Ability and willingness to provide written informed consent. Exclusion Criteria: * Age younger than 18 years. * Presence of another palmoplantar dermatosis that may interfere with the diagnosis of palmoplantar psoriasis or palmoplantar eczema. * Histopathological findings inconsistent with the clinical diagnosis, when histopathological examination was performed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Istanbul Training and Research Hospital
Istanbul, Istanbul, 34000, Turkey (Türkiye)
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Other studies related to the condition(s) this trial covers.
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