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New nasal spray aims to rapidly lift depression and suicidal urges

NCT ID NCT07193901

First seen Oct 31, 2025 · Last updated May 23, 2026 · Updated 26 times

Summary

This study tests an experimental nasal spray called (R)-Ketamine (PRT-042) to see if it can quickly reduce depression and suicidal thoughts in adults with major depressive disorder. About 98 participants will receive either the spray or a placebo, and researchers will measure changes in mood within 24 hours. The goal is to find a fast-acting treatment for people in urgent need.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • BEIjing AnDing hospital capital medical university

    RECRUITING

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Beijing AnDing hospital capital medical university

    RECRUITING

    Beijing, China

    Contact

  • Beijing Huilongguan Hospital

    RECRUITING

    Beijing, China

    Contact

  • Hangzhou Seventh People's Hospital

    RECRUITING

    Hangzhou, China

    Contact

    Contact

  • Suzhou Guangji Hospital

    RECRUITING

    Suzhou, China

    Contact

  • The Fourth People's Hospital of Chengdu

    RECRUITING

    Chengdu, China

    Contact

  • The affiliated Kangning Hospital of Ningbo University

    RECRUITING

    Ningbo, China

    Contact

  • The fourth affiliated hospital of Anhui medical university

    RECRUITING

    Hefei, China

    Contact

Conditions

Explore the condition pages connected to this study.