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New depression pill BI 1569912 put to the test in 225-Person trial

NCT ID NCT06558344

First seen May 28, 2026

Summary

This study tested whether a new oral medicine, BI 1569912, can help adults aged 18 to 65 with major depressive disorder. 225 participants were randomly assigned to one of three doses of the drug or a placebo, taken daily for 6 weeks. Researchers measured changes in depression symptoms using the MADRS scale and monitored safety. The goal was to find the right dose and see if the drug works better than placebo.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ASCLEPES Research Centers, P.C. dba Alliance Research

    Long Beach, California, 90807, United States

  • ActivMed

    Portsmouth, New Hampshire, 03801, United States

  • Adams Clinical

    Watertown, Massachusetts, 02472, United States

  • Advanced Discovery Research LLC

    Atlanta, Georgia, 30318, United States

  • Artemis Institute for Clinical Research, LLC

    San Diego, California, 92103, United States

  • Berman Clinical

    New York, New York, 10029, United States

  • Bio Behavioral Health

    Toms River, New Jersey, 08755, United States

  • Boston Clinical Trials

    Roslindale, Massachusetts, 02135, United States

  • CCM Clinical Research Group, LLC-Miami-68482

    Miami, Florida, 33133, United States

  • California Neuroscience Research

    Sherman Oaks, California, 91403, United States

  • Center For Emotional Fitness

    Cherry Hill, New Jersey, 08002, United States

  • CiTrials-Riverside-63180

    Riverside, California, 92507, United States

  • Clinical Innovations, Inc

    Bellflower, California, 90706, United States

  • Clinical Neuroscience Solutions, Inc-Jacksonville-62642

    Jacksonville, Florida, 32256, United States

  • Clinical Neuroscience Solutions, Inc-Memphis-65988

    Memphis, Tennessee, 38119, United States

  • Clinical Neuroscience Solutions, Inc-Orlando-62685

    Orlando, Florida, 32801, United States

  • Copley Clinical

    Boston, Massachusetts, 02116, United States

  • Core Clinical Research

    Everett, Washington, 98201, United States

  • Davis Clinical

    The Bronx, New York, 10461, United States

  • Excell Research Inc.

    Oceanside, California, 92056, United States

  • FutureSearch Trials of Dallas, LP

    Dallas, Texas, 75251, United States

  • Grayline Research Center

    Wichita Falls, Texas, 76309, United States

  • Hirota Clinic

    Fukuoka, Kurume, 830-0033, Japan

  • Ichigaya Himorogi Clinic

    Tokyo, Shinjuku-ku, 162-0843, Japan

  • Integrative Clinical Trials LLC

    Brooklyn, New York, 11229, United States

  • Kaku Mental Clinic

    Fukuoka, Fukuoka, 810-0022, Japan

  • Lumos Clinical Research

    San Jose, California, 95124, United States

  • Maynds Tower Mental Clinic

    Tokyo, Shibuya-ku, 151-0053, Japan

  • Neurobehavioral Research, Inc.

    Cedarhurst, New York, 11516, United States

  • Northwest Clinical Research Center

    Bellevue, Washington, 98007, United States

  • Optimus U Corporation-Miami-69452

    Miami, Florida, 33135, United States

  • Pacific Clinical Research Management Group LLC

    Upland, California, 91786, United States

  • Pharmasite Research, Incorporated

    Baltimore, Maryland, 21208, United States

  • Psych Atlanta, PC

    Marietta, Georgia, 30060, United States

  • Psychiatric Care and Research Center

    O'Fallon, Missouri, 63368, United States

  • Research Centers of America-Hollywood-67537

    Hollywood, Florida, 33024, United States

  • Sooner Clinical Research, Inc

    Oklahoma City, Oklahoma, 73116, United States

  • Surburban Research Associates, Inc.

    Media, Pennsylvania, 19063, United States

  • Uematsu Mental Clinic

    Fukuoka, Chikugo, 833-0041, Japan

  • Yutaka Clinic

    Kanagawa,Sagamihara, 252-0303, Japan

  • iResearch Atlanta

    Decatur, Georgia, 30030, United States

Conditions

The condition(s) this trial relates to.

major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.