New study seeks to boost denture hold with special adhesives
NCT ID NCT07496164
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to see if three different denture adhesive creams can help dentures stay in place better and improve bite force over 13 hours. About 60 adults aged 18 and older who wear dentures will take part. Each person will try the adhesives and also go without adhesive to compare results.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2026
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Participant provision of a signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed. * A male or female participant who, at the time of screening, is aged 18+ years. * A participant who is willing and able to comply with scheduled visits, and other study procedures. * A participant in good general and mental health with, in the opinion of the investigator or medically qualified designee, no clinically significant or relevant abnormalities in medical history or upon oral examination, or condition, that would impact the participant's safety, wellbeing or the outcome of the study, if they were to participate in the study, or affect the individual's ability to understand and follow study procedures and requirements. * A participant with a completely edentulous maxillary arch restored with a conventional maxillary full denture with an acrylic base. * A participant who is dentate in the mandibular arch or has a partial or full denture in the mandibular arch that is: 1. sufficiently stable, in the opinion of the investigator, to enable the bite force determination to be performed. 2. well made (according to the well-made assessment). Exclusion Criteria: * A participant who is an employee of the investigational site, either directly involved in the conduct of the study or a member of their immediate family; or an employee of the investigational site otherwise supervised by the investigator; or a Haleon employee directly involved in the conduct of the study or a member of their immediate family. * A participant who has participated in other studies (including non-medicinal studies) involving investigational product(s) within 30 days prior to Visit 1 and/or during study participation. * A participant who is pregnant (self-reported) or intending to become pregnant or who is breastfeeding over the duration of the study. * A participant with known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients. * A participant unwilling or unable to comply with the Lifestyle Considerations described in this protocol. * A participant who is currently taking or has taken a bisphosphonate drug. * A participant who uses any medication or has a condition that, in the opinion of the investigator, would interfere with the conduct of the study. * A participant with a recent history (within the last year) of alcohol or other substance abuse. * A participant who has previously been enrolled in this study. * A participant who, in the opinion of the investigator, is unable to comply with study requirements and/or who is not able to reliably perform a valid bite. * A participant who, in the opinion of the investigator or medically qualified designee, should not participate in the study.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Oral Health Research Institute (OHRI)
RECRUITINGIndianapolis, Indiana, 46202, United States
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