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Can a denture cream keep food out? study tests poligrip in real life

NCT ID NCT07273149

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a denture adhesive (Poligrip Power Max Hold + Seal) helps prevent food from getting trapped under dentures. 375 adults used the adhesive for three weeks and then went without it for three weeks, rating their experience daily. The goal was to see if the adhesive improves comfort during eating in everyday life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Poligrip Power Max Hold + Seal denture adhesive cream
What this could lead to
If it works, this could help denture wearers eat more comfortably with less food trapped under their dentures.
What could go wrong
This is a completed study on a marketed product, so results are already known. The main risk is that the adhesive may not work well for everyone or could cause minor irritation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

375 people

The number who actually took part.

Started

Dec 2025

Finished

May 2026

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participant's provision of a signed and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study before any assessment is performed. * Participants from all genders (male, female, not specified). * Participant who, at the time of screening is 18 years old and above. * Participants who are willing and able to comply with all study related activities as shown in the schedule of activities, study restrictions, and other study procedures. * A participant in good general and mental health with no self-reported clinically significant or relevant abnormalities in medical history or upon a previous oral examination, or condition, that would impact on the participant's safety, wellbeing or the outcome of the study, if they were to participate in the study, or affect the individual's ability to understand and follow study procedures and requirements. * A participant who is a habitual wearer of partial or full denture defined as participant who wear their dentures for the majority of their time whilst awake. * Participants should have a relatively well-fitted denture (self-assessed). * Participants who reside in the United States (except for Hawaii and Alaska). Exclusion Criteria: * An employee either directly involved in the conduct of the study or a member of their immediate family; or an employee of Lindus Health otherwise supervised by the investigator; or, a Haleon employee directly involved in the conduct of the study or a member of their immediate family. * A participant who has participated in other studies (including non-medicinal studies) involving investigational product(s) within 30 days prior to study entry and/or during study participation. * A participant who has been previously enrolled in this study. * Participants who have a clinical condition as self-reported on the screening questionnaire, which include: 1. Participants who have undergone treatment for periodontal or gum disease within 6 months of screening or are currently undergoing treatment for periodontal or gum disease. 2. Participants who have been informed by Health Care Professional (HCP) that they have active periodontitis. 3. Participants who have been informed by HCP that they have active candida infection. 4. Participants who have been informed by HCP that they have active caries. 5. Participants with any chronic and/or severe painful health condition(s) which lead to regular use of pain relief medications more than 3 days a week. 6. Participants who have any clinically significant or relevant oral abnormality (example, temporomandibular joint problems) or palate problem that could have impact on their participation in the study. 7. In the opinion of the investigator, participants with an acute or chronic medical or psychiatric condition or laboratory abnormality that may impact their safety, ability to follow study procedures or integrity of the study. * A participant who is diagnosed with xerostomia or is taking any medication that is causing xerostomia. * A participant with known or suspected intolerance or hypersensitivity to the study materials (or closely related compounds) or any of their stated ingredients. * A participant who has a recent history (within the last year) of alcohol or other substance abuse. * A participant who has history of swallowing difficulties or choking. * Participants must not receive any denture-related adjustments or treatments that alter fit, comfort or structure of their denture during the study. * Currently taking or have taken a bisphosphonate drug (that is., Fosamax, Actenol, Boniva). * A participant who reports a planned surgery during the study duration. * A participant who, in the opinion of the investigator or delegate, should not participate in the study. * A participant who is unable to read and understand English.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Lindus Health (virtual site)

    Boston, Massachusetts, 02111, United States

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