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Tooth sensitivity showdown: lasers vs. bee product gel in new study

NCT ID NCT07647861

Symptom relief Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested four approaches for treating dentine hypersensitivity (tooth sensitivity): Nd:YAG laser, diode laser, a herbal propolis-based gel, and a sham (fake) treatment. 140 adults with at least two sensitive teeth were followed for 12 months to see which method reduced pain best. The goal is to find a reliable, long-lasting solution for this common problem.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Herbal propolis-based dentin barrier agent
What this could lead to
If successful, this could point toward effective, long-lasting treatments for tooth sensitivity using lasers or natural products.
What could go wrong
This is a small, completed trial with 140 participants, so results may not apply to everyone. The sham group helps control for placebo effects, but real-world effectiveness could differ.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

140 people

The number who actually took part.

Started

Dec 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients aged between 18 and 65 years. * Presence of at least two hypersensitive teeth. * Visual Analog Scale (VAS) score of 4 or higher (VAS \>= 4) following stimulus. * Schiff Cold Air Sensitivity Scale score of 2 or higher (Schiff \>= 2). * Presence of vital teeth in the target area. * Patient is willing and able to provide written informed consent prior to study initiation. Exclusion Criteria: * Pregnancy or lactation. * Presence of active periodontal disease in the target area. * Teeth with dental caries, deep restorations, or cracked tooth syndrome. * Endodontically treated teeth. * History of allergy or hypersensitivity related to the materials, products, or chemical agents used in the study.

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Conditions

The condition(s) this trial relates to.

dentin sensitivity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dentine hypersensitivity

Contacts and locations

Locations

  • Ondokuz Mayıs University, Faculty of Dentistry, Department of Periodontology

    Samsun, Samsun, 55270, Turkey (Türkiye)

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