Can recycled tooth material help save your jawbone?
NCT ID NCT07242313
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two different graft materials made from donated teeth to see which one better preserves the jawbone after a tooth is pulled. About 45 adults needing a single upper back tooth removed will be randomly assigned to receive one of the grafts or no graft at all. Over six months, the researchers will measure bone changes using 3D X-rays and check pain, swelling, and satisfaction to find the best option before placing a dental implant.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 45 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Adults aged 18 to 60 years. Medically healthy patients classified as ASA I. Presence of a single non-restorable tooth indicated for extraction in the posterior maxilla. Adequate oral hygiene, with plaque and bleeding indices both below 20%. Sufficient bone volume to allow socket preservation without requiring simultaneous augmentation. Patients willing to participate in the study and able to provide written informed consent. Ability to commit to follow-up visits for up to 6 months. Exclusion Criteria: Smokers or tobacco users of any form. Presence of uncontrolled systemic diseases (e.g., uncontrolled diabetes). Conditions affecting bone metabolism (e.g., osteoporosis, long-term corticosteroid therapy). Pregnant or lactating women. History of radiotherapy in the head and neck region. Active infection or suppuration at the extraction site. Immunocompromised patients or those on immunosuppressive therapy. Patients taking medications known to impair healing (e.g., bisphosphonates). Allergy or hypersensitivity to any study-related materials.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Faculty of Dentistry, Kafrelsheikh University
RECRUITINGKafr ash Shaykh, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- New bone graft aims to save jawbone after tooth loss
- Dental showdown: hand vs. rotary tool for cleaner tooth sockets