Could your own tooth help a dental implant heal faster?
NCT ID NCT07610876
First seen Jun 26, 2026 · Last updated Aug 27, 2026 · Updated 3 times
Summary
This study tests whether a graft made from a patient's own tooth, combined with a melatonin gel, helps dental implants fuse better with the jawbone. Sixteen people needing a tooth extraction and immediate implant will be split into two groups. Researchers will measure implant stability, bone loss, and bone density over nine months.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Autologous demineralized dentin graft and melatonin gel
- What this could lead to
- If it works, this could improve how well and how quickly dental implants bond with the jawbone, potentially leading to more successful immediate implants.
- What could go wrong
- This is a very small early-stage trial with only 16 people, so results may not apply to everyone. The approach is also complex and may not offer significant benefit over standard care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Nov 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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20 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age above 20 years * Non-restorable maxillary premolar teeth * Candidates for immediate implant placement * Intact socket walls * Jumping gap \>2 mm * Non-smokers or light smokers * No acute infection * Adequate bone for primary stability Exclusion Criteria: * Heavy smokers * Bruxism or clenching * Uncontrolled systemic disease * Chemotherapy/radiotherapy * Immunocompromised patients
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Suez Canal University, Faculty of Dentistry
RECRUITINGIsmailia, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Laser etching could give dental implants a stronger gum seal
- Can digital scans beat molds for perfect dental implant fit?
- Which gum graft technique wins for implant health?
- Can keeping a tooth fragment save your jawbone after an implant?
- Can ceramic implants replace teeth right after extraction?